Monoclonal antibodies specific to tospoviruses
At the 1992 Annual Meeting of the American Phytopathological Society a presentation about monospecific and cross-reactive monoclonal antibodies to tospoviruses (tomato spotted wilt tospovirus, impatiens necrotic spot tospovirus - potential EPPO quarantine pests) was given. A total of 63 monoclonal antibodies specific to the nucleocapsid (N) protein, the predominant determinant in the tospovirus genus, were developed. Three MAbs with different specificities were identified for each virus as well as two MAbs which reacted equally well with both viruses and which were cross-reactive and not mixtures. Additionally, other cross-reactive MAbs were identified which detected a strain of TSWV-like virus which causes peanut bud necrosis.
Address of authors:
Department of Plant Pathology
North Carolina State University
Raleigh
27695-7616, USA
Sources
Hall, J.M. Moyer, J.W. (1992) Monospecific and cross-reactive monoclonal antibodies to tospoviruses.
Presentation at the 1992 APS/MPS Annual Meeting, Portland, OR, USA. Phytopathology 82, 1086.